| New Orleans Saints (0-1) |
| Total Net Yards | 390 |
| Penalties - Yards | 3-15 |
| Time of Possession | 32:40 |
| Total Turnovers | 1 |
| Passing | C/A | YDS | TD | INT |
| Drew Brees | 31/50 | 255 | 0 | 1 |
| Rushing | ATT | YDS | TD | LG |
| Reggie Bush | 22 | 136 | 1 | 19 |
| Mike Karney | 2 | 5 | 2 | 3 |
| Aaron Stecker | 1 | 0 | 0 | 0 |
| Drew Brees | 1 | 2 | 0 | 2 |
| Receiving | REC | YDS | TD | LG |
| Marques Colston | 12 | 107 | 0 | 29 |
| David Patten | 6 | 39 | 0 | 15 |
| Devery Henderson | 5 | 53 | 0 | 24 |
| Eric Johnson | 5 | 41 | 0 | 18 |
| Reggie Bush | 3 | 15 | 0 | 8 |
| Defense | T-A | SCK | INT | FF |
| Roman Harper | 7-0 | 1 | 0 | 0 |
| Josh Bullocks | 5-0 | 0 | 0 | 0 |
| Scott Shanle | 5-0 | 0 | 0 | 0 |
| Hollis Thomas | 4-0 | 0 | 0 | 0 |
| Mark Simoneau | 4-1 | 0 | 0 | 0 |
| Jason David | 3-2 | 0 | 0 | 0 |
| Charles Grant | 3-0 | 1 | 0 | 0 |
| Antwan Lake | 3-0 | 0 | 0 | 0 |
| Kevin Kaesviharn | 2-0 | 0 | 0 | 0 |
| Chris Reis | 2-0 | 0 | 0 | 0 |
| Mike McKenzie | 2-1 | 0 | 0 | 0 |
| Scott Fujita | 1-1 | 0 | 0 | 0 |
| Fred Thomas | 1-0 | 0 | 0 | 0 |
| Usama Young | 1-0 | 0 | 0 | 0 |
| McKinley Boykin | 1-0 | 0 | 0 | 0 |
| Renaldo Wynn | 1-0 | 0 | 0 | 0 |
| Will Smith | 1-0 | 0 | 0 | 0 |
| Brian Young | 0-0 | 0 | 0 | 0 |
| Kicking | FG | LG | XP | PTS |
| Olindo Mare | 0/1 | 0 | 3/3 | 3 |
| 3rd and 10 from their own 22 |
| Indianapolis is in a standard pass defense |
| with an extra defensive back |
| Henderson and Colston are being double-covered |
| Brees drops back to pass |
| Marques Colston is running a square out |
| Caught by Colston at the 29 |
| Then Clint Session just nails him |
| but he hangs on to the ball |
| Great catch! |
| Pushed OB straight away by Kelvin Hayden |
| after a gain of 7 yards |
| They are left with 4th and 3 |
| Game over |
| New Orleans needed a touchdown here today 28-21 |
| Indianapolis improves to 1-0 |
| New Orleans drops to 0-1 |
| Peyton Manning has been voted today's MVP |
| Passing: 361 Yds, 2 TD, 123 Rating, Rushing: 2 Yds. |
| Reggie Bush picked up 136 yards on the ground today |
| A busy day for Marques Colston who picked up 12 |
| catches |
| Injury update from Indianapolis' locker room |
| Devin Aromashodu will be out for at least 6 weeks |
| Dylan Gandy could be out for as long as a month |
| Tony Ugoh could be out for as long as a month |
| Dwight Freeney will be out for at least 6 weeks |
| Indianapolis Colts (1-0) |
| Total Net Yards | 389 |
| Penalties - Yards | 4-35 |
| Time of Possession | 27:20 |
| Total Turnovers | 0 |
| Passing | C/A | YDS | TD | INT |
| Peyton Manning | 22/33 | 361 | 2 | 0 |
| Jim Sorgi | 1/1 | 8 | 0 | 0 |
| Rushing | ATT | YDS | TD | LG |
| Joseph Addai | 14 | 20 | 0 | 7 |
| Clifton Dawson | 5 | 4 | 1 | 4 |
| Kenton Keith | 2 | -2 | 0 | 0 |
| Jim Sorgi | 1 | 2 | 0 | 2 |
| Peyton Manning | 1 | 2 | 0 | 2 |
| Dallas Clark | 1 | 14 | 0 | 14 |
| Receiving | REC | YDS | TD | LG |
| Reggie Wayne | 7 | 104 | 0 | 25 |
| Anthony Gonzalez | 4 | 84 | 0 | 47 |
| Joseph Addai | 4 | 20 | 0 | 6 |
| Marvin Harrison | 4 | 71 | 1 | 34 |
| Dallas Clark | 2 | 77 | 0 | 39 |
| Devin Aromashodu | 1 | 5 | 1 | 5 |
| Kenton Keith | 1 | 8 | 0 | 8 |
| Defense | T-A | SCK | INT | FF |
| Gary Brackett | 8-0 | 0 | 0 | 0 |
| Bob Sanders | 6-2 | 1 | 0 | 1 |
| Melvin Bullitt | 5-1 | 0 | 0 | 0 |
| Freddy Keiaho | 4-2 | 0 | 0 | 0 |
| Rocky Boiman | 4-1 | 0 | 0 | 0 |
| T.J. Rushing | 4-0 | 0 | 0 | 0 |
| Marlin Jackson | 4-0 | 0 | 0 | 0 |
| Dante Hughes | 3-1 | 0 | 0 | 0 |
| Michael Coe | 2-0 | 0 | 0 | 0 |
| Raheem Brock | 2-0 | 1 | 0 | 0 |
| Tyjuan Hagler | 2-2 | 0 | 0 | 0 |
| Kelvin Hayden | 2-1 | 0 | 0 | 0 |
| Clint Session | 1-1 | 0 | 1 | 0 |
| Antoine Bethea | 1-0 | 0 | 0 | 0 |
| Ramon Guzman | 1-0 | 0 | 0 | 0 |
| Josh Thomas | 1-0 | 0 | 0 | 0 |
| Keyunta Dawson | 1-0 | 0 | 0 | 0 |
| Brandon Archer | 1-2 | 0 | 0 | 0 |
| Ed Johnson | 1-0 | 0 | 0 | 0 |
| Dan Klecko | 1-0 | 0 | 0 | 0 |
| Matt Giordano | 1-1 | 0 | 0 | 0 |
| Robert Mathis | 1-0 | 0 | 0 | 0 |
| Tim Jennings | 0-1 | 0 | 0 | 0 |
| Jeff Charleston | 0-1 | 0 | 0 | 0 |
| Kicking | FG | LG | XP | PTS |
| Adam Vinatieri | 2/2 | 33 | 2/2 | 8 |